The goal of bone marrow transplantation is to give healthy bone marrow cells to a person after their bone marrow has been damaged due to chemotherapy. Bone marrow transplant (BMT) is only for people who have certain types of cancer or bone marrow-related illnesses. It takes stem cells from inside the bone marrow, filters them, and gives them back to the donor.
Bone marrow transplants are effective in treating various diseases. These are leukemias, lymphomas, aplastic anemia, immune deficiency disorders, and some solid tumor cancers since 1968. They have worked well.
The Need for Bone Marrow Transplantation
A bone marrow transplant aims to help people with a wide range of illnesses and types of cancer. There are times when the doses of chemotherapy or radiation needed to treat cancer are so high that a person’s bone marrow stem cells will be permanently damaged or destroyed by the treatment. So to solve this issue, a bone marrow transplant comes as a rescuer. Bone marrow transplantation also help if a disease has damaged the bone marrow and the body needs to get new bone marrow.
- It helps people to replace unhealthy bone marrow with healthy bone marrow that works.
- There may still be some cancerous cells that were not targeted by the chemotherapy or radiation. You can make a new immune system that can fight these things.
- Replace the bone marrow and get it back to work after chemotherapy and radiation treatment. This is what people call “rescue.”
- If you have Hurler’s syndrome, for example, or adrenoleukodystrophy, you can replace your bone marrow with bone marrow.
- Before you have a bone marrow transplant, talk to your doctor and experts about all the risks and benefits.
What conditions Does Bone Marrow Transplant Treat?
The doses of chemotherapy or radiation used to treat cancer are so strong that it damages the person’s stem cells. Therefore, they usually need to get a bone marrow transplant. In India, this cutting-edge procedure can be used to treat the following:
- Non-Hodgkin Lymphoma (NHL)
It’s called Non-Hodgkin Lymphoma (NHL), and it’s a type of lymphatic cancer that can be aggressive or slow to grow. People who have NHL don’t have just one disease. They have a group of diseases that are very similar.
- Hodgkin Lymphoma
Hodgkin Lymphoma is a cancer of the lymphocytes and the bone marrow, which is usually very treatable and can be cured.
- Acute Lymphocytic Leukemia (ALL)
This type of common leukemia is found in children, but it can also be found in adults. It is the most common type of leukemia in children.
- Chronic Lymphocytic Anemia (CLL)
One of the rarest types of cancer is Chronic Lymphocytic Anemia (CLL). This type grows slowly and tends to affect adults more often than children.
- Chronic Myelogenous Leukemia (CML)
This is called Chronic Myelogenous Leukemia (CML). People over 50 are most likely to get it, but it is very rare and slow-growing.
Success and Survival Rate of Bone Marrow Transplant to Cure Cancer
As of 2016, about half of people with AML who get a transplant live for more than two years. This isn’t the only thing the study found. People who had chemotherapy and a bone marrow transplant lived longer than people who had chemotherapy alone.
Most of the time, younger people are more likely to get better after they get help. 65–70 percent of people under 60 who get induction therapy will go into complete remission. This is the first phase of treatment. People over the age of 60 usually have a lower response rate, and only about 25–40% of them live for three years or more.
Also, different types of transplants may have different survival rates. Autologous transplants use cells from the person who is getting them, while allogeneic transplants use cells from someone else who is giving them.
Because allogeneic transplants are more common, autologous transplants can be an option for people with low-risk cancer who want to get a new organ.
In a 2016 study of more than 6,000 adults with AML, people who had an autologous bone marrow transplant had a 5-year survival rate of 65%. It was 62% for those who had an allogeneic bone marrow transplant.
Even though bone marrow transplants can help people live longer, they can also have serious side effects.
A source that you can trust. A doctor will talk to a person about the possible risks and benefits of a transplant when deciding on the best way to treat them.
Can a Bone Marrow Transplant Really Cure Cancer?
If you have a bone marrow transplant, the prognosis and long-term survival chances can be very different for each person. Discovery of more diseases and new medical technologies have made the results better for both children and adults. Certainly, a bone marrow transplant is effective in curing cancer. However, it is vital to choose the best hospital and surgeon to get high success.